Dual T1/T2 MRI contrast agent based on hybrid SPION@coordination polymer nanoparticles
Borges, M.; Yu, S.; Laromaine, A.; Roig, A.; Suárez-García, S.; Lorenzo, J.; Ruiz-Molina, D.; Novio, F.
RSC Advances, 5, 86779, (2015)
Abstract: We report a novel hybrid T1/T2 dual MRI contrast agent by the encapsulation of SPIONs (T2 contrast agent) into an iron-based coordination polymer with T1-weighted signal. This new hybrid material presents improved relaxometry and low cytotoxicity, which make it suitable for its use as contrast agent for MRI.