Coordination Polymers for Medical Applications: Amorphous versus Crystalline Materials

This chapter illustrates the development of coordination polymers (CPs) as novel materials for biomedical applications. We summarize the common strategies for CP synthesis and strategies to obtain crystalline or amorphous materials with interesting properties in bioimaging or drug delivery. The crystalline/amorphous nature of these materials determines many characteristics such as degradation, stability, encapsulation properties, drug delivery control, toxicity, and other physicochemical properties. Additionally, the integration of active species in CPs by physical encapsulation processes or covalent attachment allows to construct multifunctional nanostructured materials with application in drug delivery and therapy, imaging, and sensing. The main objective is to provide an outlook for the different nanosystems based on CPs and their advantages/disadvantages for a future potential clinical application.

Novio, F.; Ruiz-Molina, D.

Hybrid Organic-Inorganic Interfaces: Towards Advanced Functional Materials, Hybrid Organic-Inorganic Interfaces: Towards Advanced Functional Materials, , (2018)
DOI: 10.1002/9783527807130.ch15